ANALISIS INTERAKSI OBAT PADA PASIEN PASCA TERAPI RAWAT JALAN DI POLI SARAF RUMAH SAKIT X KOTA JAMBI

Abstrak

Potensi interaksi obat banyak dijumpai pada pasien gangguan saraf. Sistem saraf juga merupakan sistem tubuh yang banyak mendapat efek dari interaksi obat. Sebagian besar reaksi besar merugikan obat seperti interaksi obat termasuk dalam kelas organ sistem saraf.Tujuan :Mengetahui evaluasi dan hubungan karakteristik pasien dengan kejadian interaksi pada pasien rawat jalan di poli saraf. Metode: non eksperimental secara deskriptif dengan metode prospektif. Analisa data untuk melihat hubungan karaktersitik pasien dengan kejadian interaksi obat dengan uji chi square. Hasil: Jenis kelamin perempuan lebih dominan mengalami penyakit saraf sebesar (54%), Menurut usia Penderita penyakit saraf paling banyak pada usia 46-55 tahun, interaksi obat yang paling sering menimbulkan interaksi adalah kombinasi fenitoin dan diazepam, Berdasarkan tingkat keparahan interaksi obat yang tinggi pada kategori moderat sebanyak (91,17%),Mekanisme interaksi yang paling banyak adalah secara farmakodinamik sebanyak 91 kasus (89,21%). Kesimpulan : Evaluasi penggunaan obat pada pasien saraf sebanyak (14%) yang mengalami efek interaksi obat dan sebanyak (86 %) yang tidak merasakan efek interaksi obat,Diantara karakteristik pasien hanya jumlah obat yang memiliki hubungan dengan kejadian interaksi obat pada pasien pasca terapi di poli saraf.

Potential drug interactions are often found in patients with neurological disorders. The nervous system is also a body system that has many effects from drug interactions. Most of the major adverse drug reactions such as drug interactions are included in the nervous system organ class. Objective: To determine the evaluation and relationship between patient characteristics and the incidence of interactions in outpatients at the neurological polyclinic. Method: is descriptive non-experimental with a prospective method. Data analysis to see the relationship between patient characteristics and the incidence of drug interactions using the chi square test. Results: The female gender is more dominant in experiencing neurological diseases by (54%), according to age. Most neurological disease sufferers are aged 46-55 years, the drug interaction that most often causes interactions is a combination of phenytoin and diazepam, based on the high level of severity of drug interactions in the moderate category there were (91.17%), the most common interaction mechanism was pharmacodynamics in 91 cases (89.21%). Conclusion: Evaluation of drug use in neurological patients as many as (14%) experienced drug interaction effects and as many as (86%) did not experience drug interaction effects. Among the patient characteristics, only the number of drugs was related to the incidence of drug interactions in post-therapy patients at the polyclinic nerve.